If you want protection against glycation reactions and support for many aspects of health the active form of vitamin B6, pyridoxal 5'-phosphate can: Support normal function of nervous system, Promote eye and heart health, Contribute to healthy kidney function, Help prevent formation of advanced glycation end-products. Vitamin B6 is crucial in numerous life processes. Pyridoxal 5ˈ-phosphate is the metabolically active form of vitamin B6 and participates in a variety of enzymatic reactions the body.